Due to nuclear winter, the whole world is plunged into darkness. The victorious vampires have enslaved almost every human in vast camps across the globe. Among those hiding for their lives are Dr. Ephraim Goodweather, his son Zack, the veteran exterminator Vassily, and former gangbanger Gus. To be free, they must play a twisted game in which they become pawns in a battle of Good and Evil.