LEADER 00000nim a22004935a 4500 003 MWT 005 20191125031346.0 006 m o h 007 sz zunnnnnuned 007 cr nnannnuuuua 008 130915s2006 xxunnn es i n eng d 020 9781400122899 (sound recording : hoopla Audio Book) 020 1400122899 (sound recording : hoopla Audio Book) 029 https://d2snwnmzyr8jue.cloudfront.net/ ttm_9781400122899_180.jpeg 028 42 MWT10757128 037 10757128|bMidwest Tape, LLC|nhttp://www.midwesttapes.com 040 Midwest|erda 082 04 616.8/3|222 099 eAudiobook hoopla 099 eAudiobook hoopla 100 1 Max, D. T.|q(Daniel T.) 245 14 The family that couldn't sleep :|ba medical mystery |h[Hoopla electronic resource] /|cD.T. Max. 246 3 Family that could not sleep 250 Unabridged. 264 1 [United States] :|bTantor Audio,|c2006. 264 2 |bMade available through hoopla 300 1 online resource (1 audio file (540 min.)) :|bdigital. 336 spoken word|bspw|2rdacontent 337 computer|bc|2rdamedia 338 online resource|bcr|2rdacarrier 344 digital|hdigital recording|2rda 347 data file|2rda 506 Digital content provided by hoopla. 511 1 Read by Grover Gardner. 520 For two hundred years a noble Venetian family has suffered from an inherited disease that strikes their members in middle age, stealing their sleep, eating holes in their brains, and ending their lives in a matter of months. In Papua New Guinea, a primitive tribe is nearly obliterated by a sickness whose chief symptom is uncontrollable laughter. Across Europe, millions of sheep rub their fleeces raw before collapsing. In England, cows attack their owners in the milking parlors, while in the American West, thousands of deer starve to death in fields full of grass.What these strange conditions-including fatal familial insomnia, kuru, scrapie, and mad cow disease- share is their cause: prions. Prions are ordinary proteins that sometimes go wrong, resulting in neurological illnesses that are always fatal. Even more mysterious and frightening, prions are almost impossible to destroy because they are not alive and have no DNA-and the diseases they bring are now spreading around the world.In The Family That Couldn't Sleep, essayist and journalist D. T. Max tells the spellbinding story of the prion's hidden past and deadly future. Through exclusive interviews and original archival research, Max explains this story's connection to human greed and ambition-from the Prussian chemist Justus von Liebig, who made cattle meatier by feeding them the flesh of other cows, to New Guinean natives whose custom of eating the brains of the dead nearly wiped them out. The biologists who have investigated these afflictions are just as extraordinary- for example, Daniel Carleton Gajdusek, a self-described "pedagogic pedophiliac pediatrician" who cracked kuru and won the Nobel Prize, and another Nobel winner, Stanley Prusiner, a driven, feared self-promoter who identified the key protein that revolutionized prion study.With remarkable precision, grace, and sympathy, Max-who himself suffers from an inherited neurological illness-explores maladies that have tormented humanity for centuries and gives reason to hope that someday cures will be found. And he eloquently demonstrates that in our relationship to nature and these ailments, we have been our own worst enemy. 538 Mode of access: World Wide Web. 650 0 Prion diseases. 650 0 Fatal familial insomnia. 650 0 Prions. 650 0 Sleep disorders. 700 1 Gardner, Grover.|4nrt 710 2 hoopla digital. 856 40 |uhttps://www.hoopladigital.com/title/ 10757128?utm_source=MARC|zInstantly available on hoopla. 856 42 |zCover image|uhttps://d2snwnmzyr8jue.cloudfront.net/ ttm_9781400122899_180.jpeg