| Description |
1 online resource (1 volume) : illustrations. |
| Series |
Pearson always learning |
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Always learning.
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| Contents |
Cover -- Contents -- Foreword -- Preface -- Acknowledgements -- About the Author -- Chapter 1: Practical Application of Genetics in Nursing and Roles of a Nurse -- Roles of a Nurse -- Career Focus -- Review Question -- Chapter 2: Review of Cellular Division: Mitosis and Meiosis -- Introduction to Prokaryotic and Eukaryotic Cell -- Shape -- Size -- Number -- Cell wall -- Plasma membrane -- Cytoplasm -- Nucleus -- Cell Division -- An Overview of the Cell Cycle -- The Mechanics of Cell Division -- An overview of the M phase -- Cytoskeletal machines perform both mitosis and cytokinesis -- Two mechanisms help ensure that mitosis always precedes cytokinesis -- Mitosis in Detail -- Prophase -- Prometaphase -- Metaphase -- Anaphase -- Telophase -- Cytokinesis -- Meiosis -- Introduction -- Meiosis I -- Interphase I -- Prophase I -- Leptotene -- Zygotene -- Pachytene -- Diplotene -- Diakinesis -- Metaphase I -- Anaphase I -- Telophase I -- Meiosis II -- Interphase II -- Prophase II -- Metaphase II -- Anaphase II -- Review Questions -- Chapter 3: Structure and Organization of Genetic Material -- Characteristics and Structure of DNA and Chromosomes-DNA Packaging and Chromosome Condensation -- Structure of chromosomes -- Chromosomal DNA and its packaging in the chromatin fibre -- Eukaryotic DNA is packaged into a set of chromosomes -- Nucleosomes are the basic unit of eukaryotic chromosome structure -- Forms of chromosomes-metacentric, submetacentric, and acrocentric -- Chromosomes and Sex Determination -- XX-XY sex determination in humans -- The role of sex chromosomes in phenotype and fertility -- Review Questions -- Chapter 4: Errors in Transmission -- Overview of Chromosome Morphology -- Types of chromosome mutations -- Structural chromosomal abnormalities -- Chromosome rearrangements -- Duplications -- Deletions -- Inversions -- Translocations. |
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Numerical chromosomal abnormalities -- Aneuploidy -- Types of Aneuploidy -- Aneuploidy in humans -- Polyploidy -- Chromosome mutations and cancer -- Review Questions -- Chapter 5: Classical Genetics: Mendelian Theory of Inheritance -- Principles of Genetics: Mendelian Principles -- Early life of Johann Gregor Mendel (1822-1884) -- Mendel's Experimental Organism: the Pea Plant -- Mendel's Experiment: Monohybrid and Dihybrid Crosses -- Monohybrid cross -- Mendel's conclusions from the monohybrid cross -- Dihybrid cross and the principle of independent assortment -- Review Questions -- Chapter 6: Patterns and Mechanisms of Inheritance in Humans -- Pedigree -- Patterns of Inheritance in Humans -- Autosomal dominant inheritance -- Autosomal recessive inheritance -- X-linked dominant inheritance -- X-linked recessive inheritance -- Y-linked inheritance -- Mitochondrial inheritance -- Multifactorial inheritance -- Review Questions -- Chapter 7: Multiple Alleles and Blood Groups -- The ABO Blood Group -- Function of IA, IB and i Alleles of the ABO Gene -- Other Genetic Systems that Exhibit Multiple Allelism -- Review Questions -- Chapter 8: Prenatal Nutrition -- Maternal Nutritional Status -- Nutritional supplementation during pregnancy -- Physiological changes during pregnancy -- Nutritional requirements during pregnancy -- Food Allergies -- Symptoms -- Some common food allergies -- Diagnostic test available for food allergies -- Review Questions -- Chapter 9: Conditions Affecting the Mother -- Infections During Pregnancy -- Bacterial infections -- Group B beta-hemolytic streptococci (GBS) -- Group A beta-hemolytic streptococcus -- (Streptococcus pyogenes) -- Listeria monocytogenes -- Haemophilus influenzae -- Escherichia coli -- Viral infections -- Rubella -- Cytomegalovirus -- Herpes simplex virus -- Effect of Drugs, Chemicals and Radiation. |
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Effect of drugs -- Anticonvulsant drugs -- Phenytoin -- Carbamazepine -- Valproic acid -- Antidepressants -- Lithium -- Isotretinoin -- Coumarin derivatives -- Effects of alcohol -- Spontaneous abortion and stillbirths -- Low birth weight -- Neurobehavioural and neural abnormality -- Neural development -- Prevention -- Effect of chemicals -- Effects of radiation -- Radiobiology -- Effects of ionizing radiation in pregnancy -- Maternal Drug Therapy -- Review Questions -- Chapter 10: Genetic Testing and Diagnosis -- Newborn Screening -- Heterozygote Screening -- Presymptomatic Testing -- Prenatal Genetic Testing and Diagnosis -- Indications for Prenatal Diagnosis (PND) -- Methods of Prenatal Diagnosis -- Principles of Screening Tests -- Non-invasive Testing -- Ultrasound diagnosis of foetal anomalies -- Maternal serum screening -- Triple screening -- Foetal cell sorting -- Invasive Testing -- Amniocentesis -- Chorionic villus sampling -- Cordocentesis -- Preimplantation genetic diagnosis -- Review Questions -- Chapter 11: Impact of Genetic Condition on Families and Genetic Counselling -- Impact of Genetic Condition on Families -- Genetic Counselling -- Genetic services (Counselling and genetic diagnostic testing) -- Presymptomatic testing -- Carrier testing -- Prenatal testing -- Review Questions -- Chapter 12: Consanguinity -- Consanguineous Marriage and Risk of Inheriting Genetic Disorder -- Review Questions -- Chapter 13: Advanced Maternal Age -- Aneuploidies and Advanced Maternal Age -- Older egg model: In advanced maternal age -- Trisomy -- Monosomy -- Mosaicism -- Autosomal Aneuploidies -- Trisomy 21 (Down syndrome) -- Trisomy 18 (Edwards syndrome) -- Trisomy 13 (Patau syndrome) -- Sex Chromosome Aneuploidies -- Monosomy X (Turner syndrome) -- 47,XXY (Klinefelter syndrome) -- Review Questions -- Chapter 14: Down Syndrome (Trisomy 21) -- Overview. |
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Genetics of Down Syndrome -- Advanced Maternal Age in Down Syndrome -- Characteristic Features/Phenotype of Down Syndrome -- Medical Conditions Associated with Down Syndrome -- Down Syndrome Management -- Down Syndrome Diagnosis -- Prenatal screening and diagnosis -- Review Questions -- Chapter 15: Infertility -- Factors Affecting Fertility -- Causes of Subfertility-Male and Female Subfertility -- Male Subfertility -- Clinical assessment -- Treatment options for subfertile men -- Female Subfertility -- Chromosomal -- Diagnosis of anovulatory subfertility -- Management of anovulation -- Tubal subfertility -- Causes of tubal damage -- Diagnosis of tubal subfertility -- Endometriosis -- Fibroids -- Assisted Reproductive Techniques -- Review Questions -- Chapter 16: Spontaneous Abortion -- Definition -- Pathophysiology -- Potential causes of spontaneous pregnancy loss -- Mechanism of Abortion -- Incidence -- Clinical Types of Abortion -- Threatened abortion -- Inevitable abortion -- Treatment -- Incomplete abortion -- Treatment -- Complete abortion -- Treatment -- Missed abortion -- Treatment -- Septic abortion -- Treatment -- Risk of Recurrent Pregnancy Loss -- Factors Involved in Recurrent Early Pregnancy Loss -- Foetal death or disease -- Genetic Factors -- Skewed X chromosome inactivation (XCI) -- Premature centromeric division -- Non-genetic Factors -- Anatomical factors -- Endocrine factors -- Infectious factors -- Nutritional causes -- Immunological factors -- Miscellaneous Factors -- Maternal factors -- Male factors -- Indian Scenario -- Detection of recurrent abortions -- Investigation for recurrent pregnancy loss -- Review Questions -- Chapter 17: Congenital Abnormalities, Dysmorphism, and Developmental Delay -- Congenital Abnormalities (Birth Defects) and Dysmorphology -- Clinical Dysmorphology-Classification of Foetal and Birth Defects. |
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Malformation -- Deformation -- Disruption -- Dysplasia -- Diagnostic Approach to the Dysmorphic Foetus -- Single-system defect -- Syndrome -- Sequence/cascade -- Teratology -- Environmental risk parameters or modifiers -- Basic Principles of Teratology -- Developmental Milestones -- Normal development -- Developmental delay -- Diagnosis -- Identification -- Developmental disorders -- Learning disability (LD) -- Attention deficit hyperactivity disorder (ADHD)-Behavioural disorder -- Review Questions -- Chapter 18: Neural Tube Defects -- Screening of NTD with Maternal Serum Alpha-Fetoprotein (AFP) -- Ultrasound Evaluation of NTDS -- Prevention of NTD -- Genetic Susceptibility for NTD and Folic Acid Intake -- Fortification During Pregnancy -- Review Questions -- Chapter 19: The Nature of Cancer -- Cancer as a Genetic Disease -- The clonal evolution of tumours -- The role of environment in cancer -- Genes that contribute to cancer -- DNA Repair Genes -- Genes affecting chromosome segregation -- Sequences that regulate telomerase -- Genes that promote vascularization and the spread of tumours -- Chromosome Mutations and Cancer -- The Molecular Genetics of Colorectal Cancer -- Review Questions -- Chapter 20: Inborn Errors of Metabolism -- Classification of Inherited Metabolic Diseases -- Enzyme Defects (Aminoacidopathies) -- Defects in Purine Metabolism (Lesch Nyhan Syndrome) -- Lysosomal Storage Diseases -- Tay Sach's disease -- Mucopolysaccharidoses -- Chapter 21: Haematological Disorders and Genetic Haemochromatosis -- Haemoglobinopathies -- Haemolytic anemias-Sickle cell disease -- Thalassemia -- Alpha thalassemias -- Beta thalassemias -- Genetic Haemochromatosis (GH) -- Review Questions -- Chapter 22: Mental Illness/Mental Disorder -- Normal Mental Health -- Diagnosis -- Management options -- Review Questions -- Chapter 23: The Human Genome Project. |
| Summary |
Genetics for Nurses has been designed considering the syllabi requirements laid down by the Indian Nursing Council and the leading nursing colleges. The book has a variety of case studies and review questions to support the theoretical concepts and is an unique offering to the undergraduate students of nursing. |
| Subject |
Medical genetics.
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Nursing -- Study and teaching -- India.
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Genetics, Medical |
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Génétique médicale. |
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Soins infirmiers -- Étude et enseignement -- Inde. |
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Medical genetics |
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Nursing -- Study and teaching |
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India |
| ISBN |
9788131796320 |
|
8131796329 |
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8131768872 |
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9788131768877 |
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