LEADER 00000pam 2200301 i 4500 003 DLC 005 20170901113604.0 008 161220s2017 maua b 001 0 eng 010 2016058472 020 9780544716940 (hardcover) 035 (DNLM)101697675 040 DNLM/DLC|erda|cDLC|dNjBwBT|dUtOrBLW 042 pcc 092 576.5072|bDOU 100 1 Doudna, Jennifer A.,|eauthor. 245 12 A crack in creation :|bgene editing and the unthinkable power to control evolution /|cJennifer A. Doudna, Samuel H. Sternberg. 264 1 Boston :|bHoughton Mifflin Harcourt,|c2017. 300 xx, 281 pages :|billustrations ;|c24 cm 336 text|2rdacontent 337 unmediated|2rdamedia 338 volume|2rdacarrier 504 Includes bibliographical references (pages 250-269) and index. 520 Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. Not, that is, until the spring of 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the new gene-editing tool CRISPR—a revolutionary new technology that she helped create—to make heritable changes in human embryos. The cheapest, simplest, most effective way of manipulating DNA ever known, CRISPR may well give us the cure to HIV, genetic diseases, and some cancers, and will help address the world’s hunger crisis. Yet even the tiniest changes to DNA could have myriad, unforeseeable consequences—to say nothing of the ethical and societal repercussions of intentionally mutating embryos to create “better” humans. 650 0 Genetics|xResearch. 650 0 Genetic code. 700 1 Sternberg, Samuel H.,|eauthor.
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