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Author Jureidini, Jon, author.

Title The illusion of evidence-based medicine : exposing the crisis of credibility in clinical research / Jon Jureidini and Leemon B. McHenry.

Publication Info. Mile End, South Australia : Wakefield Press, 2020.
©2020
Location Call No. Status
 95th Street Adult Nonfiction  174.2951 JUR    AVAILABLE
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Description 318 pages ; 24 cm
Bibliography Includes bibliographical references and index.
Contents The crisis of credibility in clinical research -- the corruption of clinical research: Study 329 and Study CIT-MD-18 -- a rigorous conception of science in medicine -- communication of scientific findings -- academics and the corporate university -- distorted research priorities -- regulators and governance -- solutions.
Summary An expose of the corruption of medicine by the pharmaceutical industry at every level, from exploiting the vulnerable destitute for drug testing, through manipulation of research data, to disease mongering and promoting drugs that do more harm than good. Authors, Professor Jon Jureidini and Dr Leemon McHenry, made critical contributions to exposing the scientific misconduct in two infamous trials of antidepressants. Ghostwritten publications of these trials were highly influential in prescriptions of paroxetine (Paxil) and citalopram (Celexa) in paediatric and adolescent depression, yet both trials (Glaxo Smith Kline's paroxetine study 329 and Forest Laboratories' citalopram study CIT-MD-18) seriously misrepresented the efficacy and safety data. The Illusion of Evidence-Based Medicine provides a detailed account of these studies and argues that medicine desperately needs to re-evaluate its relationship with the pharmaceutical industry. Without a basis for independent evaluation of the results of randomised, placebo-controlled clinical trials, there can be no confidence in evidence-based medicine. Science demands rigorous, critical examination and especially severe testing of hypotheses to function properly, but this is exactly what is lacking in academic medicine.
Subject Evidence-based medicine.
Clinical medicine.
Pharmaceutical industry.
Medical ethics.
Clinical trials.
Conflict of interests.
Added Author McHenry, Leemon B., 1950- author.
ISBN 9781743057247 paperback
1743057245 paperback
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