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Author Khan, Iftekhar, author.

Title Design & analysis of clinical trials for economic evaluation & reimbursement : an applied approach using SAS & STATA / Iftekhar Khan. [O'Reilly electronic resource]

Publication Info. Boca Raton, FL : CRC Press, Taylor & Francis Group, [2016]
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Description 1 online resource (xxvi, 313 pages .)
Series Chapman & Hall/CRC biostatistics series
Chapman & Hall/CRC biostatistics series.
Note "Chapman & Hall book."
Bibliography Includes bibliographical references and index.
Contents 1. Introduction to economic evaluation -- 2. Health economic evaluation concepts -- 3. Designing cost-effectiveness into a clinical trial -- 4. Analysing cost data collected in a clinical trial -- 5. Quality of life in economic evaluation -- 6. Modelling in economic evaluation -- 7. Sensitivity analyses -- 8. Sample size and value of information for cost-effectiveness trials -- 9. Mixed treatment comparisons, evidence synthesis -- 10. Cost-effectiveness analyses of cancer trials -- 11. The reimbursement environment.
Summary Economic evaluation has become an essential component of clinical trial design to show that new treatments and technologies offer value to payers in various healthcare systems. Although many books exist that address the theoretical or practical aspects of cost-effectiveness analysis, this book differentiates itself from the competition by detailing how to apply health economic evaluation techniques in a clinical trial context, from both academic and pharmaceutical/commercial perspectives. It also includes a special chapter for clinical trials in Cancer. Design & Analysis of Clinical Trials for Economic Evaluation & Reimbursement is not just about performing cost-effectiveness analyses. It also emphasizes the strategic importance of economic evaluation and offers guidance and advice on the complex factors at play before, during, and after an economic evaluation. Filled with detailed examples, the book bridges the gap between applications of economic evaluation in industry (mainly pharmaceutical) and what students may learn in university courses. It provides readers with access to SAS and STATA code. In addition, Windows-based software for sample size and value of information analysis is available free of chargeґ �making it a valuable resource for students considering a career in this field or for those who simply wish to know more about applying economic evaluation techniques. The book includes coverage of trial design, case report form design, quality of life measures, sample sizes, submissions to regulatory authorities for reimbursement, Markov models, cohort models, and decision trees. Examples and case studies are provided at the end of each chapter. Presenting first-hand insights into how economic evaluations are performed from a drug development perspective, the book supplies readers with the foundation required to succeed in an environment where clinical trials and cost-effectiveness of new treatments are central. It also includes thought-provoking exercises for use in classroom and seminar discussions.-- Provided by publisher.
Subject Medical economics.
Clinical trials -- Economic aspects.
Cost effectiveness.
Clinical Trials as Topic -- economics
Cost-Benefit Analysis
Statistics as Topic
Research Design
Economics, Medical
Économie de la santé.
Études cliniques -- Aspect économique.
cost benefit analysis.
Cost effectiveness
Medical economics
Klinisches Experiment
SAS Programm
Added Title Design and analysis of clinical trials for economic evaluation and reimbursement
Other Form: Print version: Khan, Iftekhar. Design & analysis of clinical trials for economic evaluation & reimbursement. Boca Raton, FL : CRC Press, Taylor & Francis Group, [2016] 9781466505476 1466505478 (DLC) 2015021743 (OCoLC)756596310
ISBN 9781466505483 (electronic bk.)
1466505486 (electronic bk.)
Standard No. 10.1201/b19001 doi
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