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LEADER 00000cam a2200805Ia 4500
001 884966372
003 OCoLC
005 20240129213017.0
006 m o d
007 cr unu||||||||
008 140731s2014 enka ob 001 0 eng d
019 881367443
020 9781455731558
020 1455731552
020 1306859719|q(ebk)
020 9781306859714|q(ebk)
020 1455731463
020 9781455731466
029 1 DEBBG|bBV042182168
029 1 DEBSZ|b417228449
029 1 GBVCP|b882732129
029 1 AU@|b000067102652
035 (OCoLC)884966372|z(OCoLC)881367443
037 CL0500000456|bSafari Books Online
040 UMI|beng|epn|cUMI|dUIU|dIDEBK|dS4S|dDEBBG|dDEBSZ|dCOO
|dOCLCQ|dOCLCF|dCEF|dAU@|dUAB|dUKAHL|dOCLCQ|dESU|dOCLCO
|dOCLCQ|dOCLCO
049 INap
082 04 589.9047
082 04 589.9047|223
099 eBook O'Reilly for Public Libraries
245 00 Micro- and nanoengineering of the cell surface /|cedited
by Jeffrey M. Karp, Weian Zhao.|h[O'Reilly electronic
resource]
260 Oxford, UK ;|aSan Diego, CA :|bWilliam Andrew,|c©2014.
300 1 online resource :|billustrations
336 text|btxt|2rdacontent
337 computer|bc|2rdamedia
338 online resource|bcr|2rdacarrier
490 1 Micro & nano technologies series
504 Includes bibliographical references and index.
505 0 Front Cover; Micro- and Nanoengineering of the Cell
Surface; Copyright Page; Contents; Foreword; List of
Contributors; 1 Cell Membrane Biology and Juxtacrine
Signal Conversion; 1.1 Introduction; 1.2 Cell membrane
biology-early milestones; 1.3 Membrane microdomains; 1.4
Cell membrane emergence; 1.5 Juxtacrine signaling and
rewiring cellular networks; 1.6 Protein painting,
artificial veto cell engineering; 1.7 Trans signal
conversion; 1.8 Redirecting juxtacrine signals; 1.9
Creating auto-signaling loops; 1.10 SCP therapeutic
flexibility; 1.11 The cell membrane frontier; References.
505 8 2 Cell Surface Engineering by Chemical Reaction and
Remodeling2.1 Introduction; 2.2 Methods and technology of
covalent cell surface reaction; 2.2.1 Direct chemical
modification of cell membrane; 2.2.2 Indirect chemical
modification of cell membrane; 2.3 Relevance of covalent
cell surface modification; 2.4 Future perspectives; 2.5
Conclusions; References; 3 Bioconjugation Reactions in
Living Cells: Development, Advances, and Applications of
Glycan-Specific Technologies; 3.1 Introduction; 3.2
Bioorthogonal chemical ligation reactions for glycan
labeling.
505 8 3.2.1 Aldehyde- and Ketone-Based Bioorthogonal
Reactions3.2.1.1 Aldehyde-Based Reactions; 3.2.1.2
Metabolic Incorporation Expands Bioorthogonal Ligation to
Include Ketone-Based Reactions; 3.2.2 Azide- and Alkyne-
Based Bioorthogonal Reactions; 3.2.2.1 Classical and
Modified Staudinger Ligation Reactions; 3.2.2.2 Click
Reactions: the Copper-Catalyzed [3+2] Azide-Alkyne
Cycloaddition; 3.2.2.3 Strain-Promoted Azide-Alkyne
Cycloaddition Reactions; 3.2.3 Thiol-based Chemistry;
3.2.4 Photoactivated Ligation Reactions; 3.2.4.1
Benzophenones; 3.2.4.2 Arylazides; 3.2.4.3 Diazirines.
505 8 3.3 Bioorthogonal ligation reactions: exploitation in MOE-
based applications3.3.1 MOE Extends Beyond N-Acyl-Modified
Sialic Acid; 3.3.2 Imaging of Living Cells; 3.3.3 In vivo
Labeling/Imaging; 3.3.4 Tissue Engineering, Stem Cell
Research, and Regenerative Medicine; 3.3.5 Cancer Therapy;
3.4 Concluding comments; References; 4 Pushing the
Bacterial Envelope: Strategies for Re-Engineering
Bacterial Surfaces with Heterologous Proteins and Sugars;
4.1 Bacterial surface display; 4.2 Strategies for re-
engineering bacterial surfaces with heterologous proteins;
4.2.1 Gram-Negative Organisms.
505 8 4.2.2 Gram-Positive Organisms4.2.3 Spores; 4.2.4 Outer
Membrane Vesicles and Bacterial Ghosts; 4.3 Applications
of bacteria expressing heterologous surface proteins;
4.3.1 Vaccines Against Infectious Disease; 4.3.2
Anticancer Therapeutics; 4.3.3 Vaccines Against Cancer;
4.3.4 Biocatalysis; 4.3.5 Interactions Between Surface
Proteins and Solutes; 4.3.5.1 Biosensing: Binding for
Purposes of Detection; 4.3.5.2 Biosorption: Binding for
Purposes of Purification; 4.3.5.3 Screening: Binding for
Purposes of Identification; 4.4 Strategies for re-
engineering bacterial surfaces with heterologous sugars.
520 Micro- and Nanoengineering of the Cell Surface explores
the direct engineering of cell surfaces, enabling
materials scientists and chemists to manipulate or augment
cell functions and phenotypes. The book is accessible for
readers across industry, academia, and in clinical
settings in multiple disciplines, including materials
science, engineering, chemistry, biology, and medicine.
Written by leaders in the field, it covers numerous cell
surface engineering methods along with their current and
potential applications in cell therapy, tissue engineering,
biosensing, and diagnosis.>
588 0 Online resource; title from title page (Safari, viewed
July 2, 2014).
590 O'Reilly|bO'Reilly Online Learning: Academic/Public
Library Edition
650 0 Biomedical engineering.
650 0 Nanotechnology.
650 0 Cells|xMicrobiology.
650 0 Ultrastructure (Biology)
650 0 Bacterial cell surfaces.
650 2 Nanotechnology
650 6 Génie biomédical.
650 6 Cellules|xMicrobiologie.
650 6 Ultrastructure (Biologie)
650 6 Surface bactérienne.
650 6 Nanotechnologie.
650 7 biomedical engineering.|2aat
650 7 ultrastructure.|2aat
650 7 Bacterial cell surfaces|2fast
650 7 Biomedical engineering|2fast
650 7 Nanotechnology|2fast
650 7 Ultrastructure (Biology)|2fast
700 1 Karp, Jeffrey M.
700 1 Zhao, Weian.
776 08 |iPrint version:|z9781306859714
830 0 Micro & nano technologies.
856 40 |uhttps://ezproxy.naperville-lib.org/login?url=https://
learning.oreilly.com/library/view/~/9781455731466/?ar
|zAvailable on O'Reilly for Public Libraries
938 Askews and Holts Library Services|bASKH|nAH25543898
938 ProQuest MyiLibrary Digital eBook Collection|bIDEB
|ncis28460754
994 92|bJFN