Implementation strategies -- SDTM metadata and Define.xml for base SAS implementation -- Implementing the CDISC SDTM with base SAS -- Implementing CDISC SDTM with the SAS clinical standards toolkit and base SAS -- Implementing the CDISC SDTM with SAS clinical data integration -- ADaM metadata and ADaM Define.xml -- Implementing ADaM with base SAS -- CDISC validation using SAS -- CDISC validation using Pinnacle 21 community -- CDISC data review and analysis -- Integrated data and regulatory submissions -- Other topics.